Spatial structure facilitates cooperation inside a social dilemma: empirical evidence from a bacterial community
It was only during the 1990s while, when nanotechnology had Innovative to a stage where by solitary molecules can be manipulated, that the primary experimental devices started to look.
[Laughs] ‘It had been absolutely an incredible possibility! At enough time, I had been very well informed that it could go Completely wrong Which I could develop into significantly less prosperous, but I just overlooked that. Curiosity has often been my strongest driving power. And fortuitously it all labored out.’
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
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SMC complexes can go Actual physical roadblocks larger than their ring size, indicating a nontopological mechanism for DNA loop extrusion
We use nanofabricated microfluidic structures to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental job of spatial confinement within the molecular and mobile amount. Our initiatives include things like the subsequent:
Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation
In 1993, to be a young and eager affiliate professor at Delft University of Technological innovation, I'd at first centered the research initiatives of ceesdekker.net my team on measuring the electrical conductance of a single conducting-polymer molecule. In two decades, we had developed a tool in which just one wire of a phthalocyaninepolysiloxane polymer was linked between two closely spaced steel nanoelectrodes.
Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding because the stage-producing method
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Nanoscientist Cees Dekker can be an amiable and flamboyant person who seems Substantially youthful as opposed to 62 several years he in fact is – stylish Eyeglasses, psychedelic shirt, partaking smile – although not one particular to waste time. He requires his time, but no more than necessary.
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2013, controlled shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations while in the handedness of histone tetrasomes